POLR1D antibody (AA 10-133) (HRP)

Catalog No. ABIN8024248

The HRP-conjugated Rabbit Polyclonal anti-POLR1D antibody (ABIN8024248) specifically detects POLR1D in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for POLR1D antibody (AA 10-133) (HRP) (ABIN8024248)

Target: POLR1D (Polymerase (RNA) I Polypeptide D, 16kDa (POLR1D))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR1D antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-POLR1D Antibody (HRP)

Binding Specificity: AA 10-133

Purpose: Anti-POLR1D Antibody HRP Conjugated

Predicted Reactivity: Human POLR1D shares 90.3% amino acid (aa) sequence identity with mouse POLR1D.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human POLR1D recombinant protein (Position: K10-F133). Human POLR1D shares 90.3% amino acid (aa) sequence identity with mouse POLR1D.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for POLR1D

Target: POLR1D (Polymerase (RNA) I Polypeptide D, 16kDa (POLR1D))

Alternative Name: POLR1D

Background:

Background: DNA-ed RNA polymerases I and III subunit RPAC2 is a protein that in humans is encoded by the POLR1D gene. The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants.

Gene Full Name: RNA polymerase I and III subunit D

Gene ID: 51082

UniProt: P0DPB6