POLR2D antibody (AA 7-124) (Cy3)

Catalog No. ABIN8024276

This Rabbit Polyclonal antibody specifically detects POLR2D in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for POLR2D antibody (AA 7-124) (Cy3) (ABIN8024276)

Target: POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR2D antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-POLR2D Antibody (Cy3)

Binding Specificity: AA 7-124

Purpose: Anti-POLR2D Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human POLR2D recombinant protein (Position: D7-D124).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for POLR2D

Target: POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))

Alternative Name: POLR2D

Background:

Background: DNA-ed RNA polymerase II subunit RPB4 is an enzyme that in humans is encoded by the POLR2D gene. This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene.

Gene Full Name: RNA polymerase II subunit D

Gene ID: 5433

UniProt: O15514

Pathways: Regulatory RNA Pathways