PIGR antibody (C-Term) (APC)

Catalog No. ABIN8024371

The APC-conjugated Rabbit Polyclonal anti-PIGR antibody (ABIN8024371) specifically detects PIGR in FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for PIGR antibody (C-Term) (APC) (ABIN8024371)

Target: PIGR (Polymeric Immunoglobulin Receptor (PIGR))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGR antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-PIGR Antibody (APC)

Binding Specificity: C-Term

Purpose: Anti-PIGR Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related rat sequence by eighteen amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human PIGR, different from the related rat sequence by eighteen amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PIGR

Target: PIGR (Polymeric Immunoglobulin Receptor (PIGR))

Alternative Name: PIGR

Background:

Background: Polymeric immunoglobulin receptor is a protein that in humans is encoded by the PIGR gene. It is a Fc receptor which facilitates the secretion of the soluble polymeric isoforms of immunoglobulin A and immunoglobulin M. This gene is mapped to 1q31-q41. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells, the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.

Gene Full Name: polymeric immunoglobulin receptor

Gene ID: 5284

UniProt: P01833