PNKP antibody (AA 43-487) (HRP)

Catalog No. ABIN8024392

The HRP-conjugated Rabbit Polyclonal anti-PNKP antibody (ABIN8024392) specifically detects PNKP in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PNKP antibody (AA 43-487) (HRP) (ABIN8024392)

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNKP antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PNKP Antibody (HRP)

Binding Specificity: AA 43-487

Purpose: Anti-PNKP Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PNKP shares 81.8% amino acid (aa) sequence identity with mouse PNKP.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PNKP recombinant protein (Position: D43-E487). Human PNKP shares 81.8% amino acid (aa) sequence identity with mouse PNKP.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PNKP

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Alternative Name: PNKP

Background:

Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Gene Full Name: polynucleotide kinase 3'-phosphatase

Gene ID: 11284

UniProt: Q96T60

Pathways: DNA Damage Repair, Nucleotide Phosphorylation