PTCRA antibody (AA 24-143) (Biotin)

Catalog No. ABIN8025017

This Rabbit Polyclonal antibody specifically detects PTCRA in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for PTCRA antibody (AA 24-143) (Biotin) (ABIN8025017)

Target: PTCRA (Pre T-Cell Antigen Receptor alpha (PTCRA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTCRA antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PTCRA Antibody (Biotin)

Binding Specificity: AA 24-143

Purpose: Anti-PTCRA Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human PTCRA recombinant protein (Position: T24-T143).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PTCRA

Target: PTCRA (Pre T-Cell Antigen Receptor alpha (PTCRA))

Alternative Name: PTCRA

Background:

Background: This PTCRA gene is mapped to 6p21.1. The protein encoded by this gene is a single-pass type I membrane protein that is found in immmature but not mature T-cells. Along with TCRB and CD3 complex, the encoded protein forms the pre-T-cell receptor complex, which regulates early T-cell development. Four transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: pre T cell antigen receptor alpha

Gene ID: 171558

UniProt: Q6ISU1

Pathways: Cancer Immune Checkpoints