PD-1 antibody (N-Term) (HRP)

Catalog No. ABIN8025524

This Rabbit Polyclonal antibody specifically detects PD-1 in IHC, WB and ELISA. It exhibits reactivity toward Mouse and Rat.

Quick Overview for PD-1 antibody (N-Term) (HRP) (ABIN8025524)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PD-1 antibody is conjugated to HRP

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Product Details anti-PD-1 Antibody (HRP)

Binding Specificity: N-Term

Purpose: Anti-PD-1/PDCD1 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related human sequence by fifteen amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse PD1, different from the related human sequence by fifteen amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Alternative Name: PDCD1

Background:

Background: Transcription factor SOX-9 is a protein that in humans is encoded by the SOX9 gene. The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

Gene Full Name: programmed cell death 1

Gene ID: 18566

UniProt: Q02242

Pathways: Cancer Immune Checkpoints