slc25a13 antibody (AA 351-450)

Catalog No. ABIN752908

This Rabbit Polyclonal antibody specifically detects slc25a13 in WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for slc25a13 antibody (AA 351-450) (ABIN752908)

Target: slc25a13 (Solute Carrier Family 25, Member 13 (Citrin) (slc25a13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This slc25a13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-slc25a13 Antibody

Binding Specificity: AA 351-450

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLC25A13

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for slc25a13

Target: slc25a13 (Solute Carrier Family 25, Member 13 (Citrin) (slc25a13))

Alternative Name: SLC25A13

Background:

Synonyms: ARALAR2, Calcium binding mitochondrial carrier protein Aralar2, Citrin, CTLN2, Ctrn, Mitochondrial aspartate glutamate carrier 2, RGD1565889, Solute carrier family 25 citrin member 13, Solute carrier family 25 member 13 citrin, Solute carrier family 25 member 13, AI785475, CMC2_HUMAN.

Background: SLC25A13 is a member of the mitochondrial carrier family. It contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. It catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in the SLC25A13 gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID: 10165

Pathways: Ribonucleoside Biosynthetic Process, Dicarboxylic Acid Transport