PSMA5 antibody (AA 1-241) (HRP)

Catalog No. ABIN8026952

This Rabbit Polyclonal antibody specifically detects PSMA5 in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for PSMA5 antibody (AA 1-241) (HRP) (ABIN8026952)

Target: PSMA5 (Proteasome Subunit alpha 5 (PSMA5))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA5 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PSMA5 Antibody (HRP)

Binding Specificity: AA 1-241

Purpose: Anti-PSMA5 Antibody HRP Conjugated

Predicted Reactivity: Human PSMA5 shares 100%,98.8% amino acid (aa) sequence identity with mouse,rat PSMA5,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PSMA5 recombinant protein (Position: M1-I241). Human PSMA5 shares 100% and 98.8% amino acid (aa) sequence identity with mouse and rat PSMA5, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PSMA5

Target: PSMA5 (Proteasome Subunit alpha 5 (PSMA5))

Alternative Name: PSMA5

Background:

Background: Proteasome subunit alpha type-5 also known as 20S proteasome subunit alpha-5 is a protein that in humans is encoded by the PSMA5 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene.

Gene Full Name: proteasome 20S subunit alpha 5

Gene ID: 5686

UniProt: P28066

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA