PRMT1 antibody (AA 11-145) (PE)

Catalog No. ABIN8027066

This Rabbit Polyclonal antibody specifically detects PRMT1 in FACS. It exhibits reactivity toward Human.

Quick Overview for PRMT1 antibody (AA 11-145) (PE) (ABIN8027066)

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-PRMT1 Antibody (PE)

Binding Specificity: AA 11-145

Purpose: Anti-PRMT1 Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PRMT1 recombinant protein (Position: M11-K145).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PRMT1

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Alternative Name: PRMT1

Background:

Background: Protein arginine N-methyltransferase 1?is an?enzyme?that in humans is encoded by the?PRMT1?gene. It is mapped to 19q13.33. This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

Gene Full Name: protein arginine methyltransferase 1

Gene ID: 3276

UniProt: Q99873