PPP1R3C antibody (Middle Region)
Quick Overview for PPP1R3C antibody (Middle Region) (ABIN8027964)
Target
See all PPP1R3C AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Binding Specificity
- Middle Region
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Purpose
- Anti-PPP1R3C Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Characteristics
- Anti-PPP1R3C Antibody. Tested in WB applications. This antibody reacts with Rat.
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Purification
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human PPP1R3C.
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Isotype
- IgG
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Application Notes
- Western blot, 0.25-0.5 μg/mL, Rat
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing. -
Expiry Date
- 12 months
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- PPP1R3C (Protein Phosphatase 1, Regulatory Subunit 3C (PPP1R3C))
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Alternative Name
- PPP1R3C
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Background
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Background: This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease.
Gene Full Name: protein phosphatase 1 regulatory subunit 3C
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Molecular Weight
- 38 kDa
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Gene ID
- 5507
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UniProt
- Q9UQK1
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Pathways
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
Target
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