SPDEF/PSE antibody (AA 52-335) (Biotin)

Catalog No. ABIN8028780

The Rabbit Polyclonal anti-SPDEF/PSE antibody is suitable to detect SPDEF/PSE in samples from Human. It has been validated for ELISA, WB and IHC.

Quick Overview for SPDEF/PSE antibody (AA 52-335) (Biotin) (ABIN8028780)

Target: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPDEF/PSE antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SPDEF/PSE Antibody (Biotin)

Binding Specificity: AA 52-335

Purpose: Anti-PSE/SPDEF Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PSE/SPDEF recombinant protein (Position: E52-I335).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SPDEF/PSE

Target: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Alternative Name: SPDEF

Background:

Background: SAM pointed domain-containing Ets transcription factor is a protein that in humans is encoded by the SPDEF gene. The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: SAM pointed domain containing ETS transcription factor

Gene ID: 25803

UniProt: O95238