QDPR antibody (Middle Region) (PE)

Catalog No. ABIN8029494

The Rabbit Polyclonal anti-QDPR antibody is suitable to detect QDPR in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for QDPR antibody (Middle Region) (PE) (ABIN8029494)

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QDPR antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-QDPR Antibody (PE)

Binding Specificity: Middle Region

Purpose: Anti-QDPR Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human QDPR.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for QDPR

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Alternative Name: QDPR

Background:

Background: This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Gene Full Name: quinoid dihydropteridine reductase

Gene ID: 5860

UniProt: P09417