QDPR antibody (Middle Region)

Catalog No. ABIN8029496

This Rabbit Polyclonal antibody specifically detects QDPR in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for QDPR antibody (Middle Region) (ABIN8029496)

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QDPR antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-QDPR Antibody

Binding Specificity: Middle Region

Purpose: Anti-QDPR Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-QDPR Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human QDPR.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for QDPR

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Alternative Name: QDPR

Background:

Background: This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Gene Full Name: quinoid dihydropteridine reductase

Molecular Weight: 26 kDa

Gene ID: 5860

UniProt: P09417