RAB13 antibody (C-Term) (Fluoro594)

Catalog No. ABIN8029611

The Rabbit Polyclonal anti-RAB13 antibody is suitable to detect RAB13 in samples from Human. It has been validated for FACS.

Quick Overview for RAB13 antibody (C-Term) (Fluoro594) (ABIN8029611)

Target: RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB13 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-RAB13 Antibody (Fluoro594)

Binding Specificity: C-Term

Purpose: Anti-RAB13 Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse,rat sequences by four amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human RAB13, different from the related mouse and rat sequences by four amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RAB13

Target: RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Alternative Name: RAB13

Background:

Background: Ras-related protein Rab-13 is a protein that in humans is encoded by the RAB13 gene. This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12.

Gene Full Name: RAB13, member RAS oncogene family

Gene ID: 5872

UniProt: P51153

Pathways: Cell-Cell Junction Organization