RAB7A antibody (AA 21-177) (Fluoro647)

Catalog No. ABIN8029972

The Fluoro647-conjugated Rabbit Polyclonal anti-RAB7A antibody (ABIN8029972) specifically detects RAB7A in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RAB7A antibody (AA 21-177) (Fluoro647) (ABIN8029972)

Target: RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB7A antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-RAB7A Antibody (Fluoro647)

Binding Specificity: AA 21-177

Purpose: Anti-RAB7/RAB7A Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RAB7/RAB7A recombinant protein (Position: K21-E177).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RAB7A

Target: RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))

Alternative Name: RAB7A

Background:

Background: Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. RAB7A functions as a key regulator in endo-lysosomal trafficking, governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end ed endosomal migration and positions, and endosome-lysosome transport through different protein-protein interaction cascades. Furthermore, RAB7A is involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes through modulation of SOX10 and the oncogene MYC. Mutations in the lysosomal pathway result in tumor progression in melanoma cells.

Gene Full Name: RAB7A, member RAS oncogene family

Gene ID: 7879

UniProt: P51149

Pathways: EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome