RGS6 antibody (AA 7-357) (PE)

Catalog No. ABIN8031164

This Rabbit Polyclonal antibody specifically detects RGS6 in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for RGS6 antibody (AA 7-357) (PE) (ABIN8031164)

Target: RGS6 (Regulator of G-Protein Signaling 6 (RGS6))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS6 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-RGS6 Antibody (PE)

Binding Specificity: AA 7-357

Purpose: Anti-RGS6 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RGS6 recombinant protein (Position: D7-E357).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RGS6

Target: RGS6 (Regulator of G-Protein Signaling 6 (RGS6))

Alternative Name: RGS6

Background:

Background: Regulator of G-protein signaling 6 is a protein that in humans is encoded by the RGS6 gene. This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.

Gene Full Name: regulator of G protein signaling 6

Gene ID: 9628

UniProt: P49758

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling