RNH1 antibody (N-Term) (Fluoro594)

Catalog No. ABIN8032408

The Fluoro594-conjugated Mouse Monoclonal anti-RNH1 antibody (Clone 4F3) (ABIN8032408) specifically detects RNH1 in FACS. The antibody is reactive with Human samples.

Quick Overview for RNH1 antibody (N-Term) (Fluoro594) (ABIN8032408)

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RNH1 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Clone: 4F3

Product Details anti-RNH1 Antibody (Fluoro594)

Binding Specificity: N-Term

Purpose: Anti-Ribonuclease Inhibitor/RNH1 Antibody (monoclonal, 4F3) Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by five amino acids,and from the related rat sequence by four amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human RNH1, different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RNH1

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Alternative Name: RNH1

Background:

Background: Ribonuclease inhibitor is an enzyme that in humans is encoded by the RNH1 gene. Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular Rnases. In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin. Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover, the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.

Gene Full Name: ribonuclease/angiogenin inhibitor 1

Gene ID: 6050

UniProt: P13489