RING1 antibody (AA 6-387) (PE)

Catalog No. ABIN8033160

The Rabbit Polyclonal anti-RING1 antibody is suitable to detect RING1 in samples from Human and Rat. It has been validated for FACS.

Quick Overview for RING1 antibody (AA 6-387) (PE) (ABIN8033160)

Target: RING1 (Ring Finger Protein 1 (RING1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RING1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-RING1 Antibody (PE)

Binding Specificity: AA 6-387

Purpose: Anti-RING1 Antibody PE Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human RING1 shares 96.3%,96.6% amino acid (aa) sequence identity with mouse,rat RING1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RING1 recombinant protein (Position: N6-K387). Human RING1 shares 96.3% and 96.6% amino acid (aa) sequence identity with mouse and rat RING1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RING1

Target: RING1 (Ring Finger Protein 1 (RING1))

Alternative Name: RING1

Background:

Background: E3 ubiquitin-protein ligase RING1 is an enzyme that in humans is encoded by the RING1 gene. This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

Gene Full Name: ring finger protein 1

Gene ID: 6015

UniProt: Q06587