RLIM antibody (AA 369-621) (Cy3)

Catalog No. ABIN8033395

The Cy3-conjugated Rabbit Polyclonal anti-RLIM antibody (ABIN8033395) specifically detects RLIM in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RLIM antibody (AA 369-621) (Cy3) (ABIN8033395)

Target: RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RLIM antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-RLIM Antibody (Cy3)

Binding Specificity: AA 369-621

Purpose: Anti-RLIM Antibody Cy3 Conjugated

Predicted Reactivity: Human RLIM shares 95.4% amino acid (aa) sequence identity with mouse RLIM.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RLIM recombinant protein (Position: R369-E621). Human RLIM shares 95.4% amino acid (aa) sequence identity with mouse RLIM.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RLIM

Target: RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))

Alternative Name: RLIM

Background:

Background: E3 ubiquitin-protein ligase RLIM is an enzyme that in humans is encoded by the RLIM gene. The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Full Name: ring finger protein, LIM domain interacting

Gene ID: 51132

UniProt: Q9NVW2