RLIM antibody (AA 369-621) (HRP)

Catalog No. ABIN8033400

The Rabbit Polyclonal anti-RLIM antibody is suitable to detect RLIM in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for RLIM antibody (AA 369-621) (HRP) (ABIN8033400)

Target: RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RLIM antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RLIM Antibody (HRP)

Binding Specificity: AA 369-621

Purpose: Anti-RLIM Antibody HRP Conjugated

Predicted Reactivity: Human RLIM shares 95.4% amino acid (aa) sequence identity with mouse RLIM.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RLIM recombinant protein (Position: R369-E621). Human RLIM shares 95.4% amino acid (aa) sequence identity with mouse RLIM.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RLIM

Target: RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))

Alternative Name: RLIM

Background:

Background: E3 ubiquitin-protein ligase RLIM is an enzyme that in humans is encoded by the RLIM gene. The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Full Name: ring finger protein, LIM domain interacting

Gene ID: 51132

UniProt: Q9NVW2