SCO2 antibody (AA 29-266) (Biotin)

Catalog No. ABIN8034823

The Biotin-conjugated Rabbit Polyclonal anti-SCO2 antibody (ABIN8034823) specifically detects SCO2 in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for SCO2 antibody (AA 29-266) (Biotin) (ABIN8034823)

Target: SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCO2 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-SCO2 Antibody (Biotin)

Binding Specificity: AA 29-266

Purpose: Anti-SCO2 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SCO2 shares 87.6% amino acid (aa) sequence identity with mouse SCO2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SCO2 recombinant protein (Position: Q29-S266). Human SCO2 shares 87.6% amino acid (aa) sequence identity with mouse SCO2.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SCO2

Target: SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))

Alternative Name: SCO2

Background:

Background: Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors, this gene encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy and myopia 6.

Gene Full Name: synthesis of cytochrome C oxidase 2

Gene ID: 9997

UniProt: O43819

Pathways: Transition Metal Ion Homeostasis, Warburg Effect