SCYL1 antibody (AA 5-259) (APC)

Catalog No. ABIN8034852

The Rabbit Polyclonal anti-SCYL1 antibody is suitable to detect SCYL1 in samples from Human. It has been validated for FACS.

Quick Overview for SCYL1 antibody (AA 5-259) (APC) (ABIN8034852)

Target: SCYL1 (SCY1-Like 1 (SCYL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCYL1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-SCYL1 Antibody (APC)

Binding Specificity: AA 5-259

Purpose: Anti-SCYL1 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SCYL1 recombinant protein (Position: A5-Q259).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SCYL1

Target: SCYL1 (SCY1-Like 1 (SCYL1))

Alternative Name: SCYL1

Background:

Background: SCY1-like 1 (S. cerevisiae), also known as SCYL1, is a human gene which is highly conserved throughout evolution. This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: SCY1 like pseudokinase 1

Gene ID: 57410

UniProt: Q96KG9

Pathways: p53 Signaling