SCYL2 antibody (AA 208-909) (HRP)

Catalog No. ABIN8034862

The HRP-conjugated Rabbit Polyclonal anti-SCYL2 antibody (ABIN8034862) specifically detects SCYL2 in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for SCYL2 antibody (AA 208-909) (HRP) (ABIN8034862)

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCYL2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SCYL2 Antibody (HRP)

Binding Specificity: AA 208-909

Purpose: Anti-SCYL2 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SCYL2 recombinant protein (Position: E208-Q909).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SCYL2

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Alternative Name: SCYL2

Background:

Background: SCY1-like protein 2 is a protein that in humans is encoded by the SCYL2 gene. The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene.

Gene Full Name: SCY1 like pseudokinase 2

Gene ID: 55681

UniProt: Q6P3W7