SCYL2 antibody (AA 208-909) (PE)

Catalog No. ABIN8034864

The Rabbit Polyclonal anti-SCYL2 antibody is suitable to detect SCYL2 in samples from Human. It has been validated for FACS.

Quick Overview for SCYL2 antibody (AA 208-909) (PE) (ABIN8034864)

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCYL2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-SCYL2 Antibody (PE)

Binding Specificity: AA 208-909

Purpose: Anti-SCYL2 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SCYL2 recombinant protein (Position: E208-Q909).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SCYL2

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Alternative Name: SCYL2

Background:

Background: SCY1-like protein 2 is a protein that in humans is encoded by the SCYL2 gene. The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene.

Gene Full Name: SCY1 like pseudokinase 2

Gene ID: 55681

UniProt: Q6P3W7