Senataxin (SETX) (AA 29-2544) antibody (HRP)

Catalog No. ABIN8035622

This Rabbit Polyclonal antibody specifically detects Senataxin in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Senataxin (SETX) (AA 29-2544) antibody (HRP) (ABIN8035622)

Target: Senataxin (SETX)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 29-2544

Purpose: Anti-SETX Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SETX shares 72.8% amino acid (aa) sequence identity with mouse SETX.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SETX recombinant protein (Position: E29-R2544). Human SETX shares 72.8% amino acid (aa) sequence identity with mouse SETX.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: Senataxin (SETX)

Alternative Name: SETX

Background:

Background: This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4).

Gene Full Name: senataxin

Gene ID: 23064

UniProt: Q7Z333