Senataxin (SETX) (AA 29-2544) antibody (PE)

Catalog No. ABIN8035624

The PE-conjugated Rabbit Polyclonal anti-Senataxin antibody (ABIN8035624) specifically detects Senataxin in FACS. The antibody is reactive with Human samples.

Quick Overview for Senataxin (SETX) (AA 29-2544) antibody (PE) (ABIN8035624)

Target: Senataxin (SETX)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: PE

Application: Flow Cytometry (FACS)

Product Details

Binding Specificity: AA 29-2544

Purpose: Anti-SETX Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SETX shares 72.8% amino acid (aa) sequence identity with mouse SETX.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SETX recombinant protein (Position: E29-R2544). Human SETX shares 72.8% amino acid (aa) sequence identity with mouse SETX.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details

Target: Senataxin (SETX)

Alternative Name: SETX

Background:

Background: This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4).

Gene Full Name: senataxin

Gene ID: 23064

UniProt: Q7Z333