Senataxin (SETX) (AA 28-2447) antibody (HRP)

Catalog No. ABIN8035633

The HRP-conjugated Rabbit Polyclonal anti-Senataxin antibody (ABIN8035633) specifically detects Senataxin in WB, ELISA and IHC. The antibody is reactive with Mouse and Rat samples.

Quick Overview for Senataxin (SETX) (AA 28-2447) antibody (HRP) (ABIN8035633)

Target: Senataxin (SETX)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 28-2447

Purpose: Anti-SETX Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse SETX shares 72.8% amino acid (aa) sequence identity with humanSETX.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse SETX recombinant protein (Position: S28-R2447). Mouse SETX shares 72.8% amino acid (aa) sequence identity with humanSETX.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: Senataxin (SETX)

Alternative Name: SETX

Background:

Background: Predicted to enable RNA binding activity, identical protein binding activity, and transcription termination site sequence-specific DNA binding activity. Acts upstream of or within circadian rhythm and termination of RNA polymerase II transcription. Predicted to be located in several cellular components, including growth cone, intercellular bridge, and nuclear lumen. Predicted to be active in nuclear body. Is expressed in cerebral cortex ventricular layer and cortical plate. Used to study amyotrophic lateral sclerosis type 4. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 4 and spinocerebellar ataxia with axonal neuropathy 2. Orthologous to human SETX (senataxin).

Gene Full Name: senataxin

Gene ID: 269254

UniProt: A2AKX3