Senataxin (SETX) (AA 28-2447) antibody (Fluoro647)

Catalog No. ABIN8035636

The Fluoro647-conjugated Rabbit Polyclonal anti-Senataxin antibody (ABIN8035636) specifically detects Senataxin in FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for Senataxin (SETX) (AA 28-2447) antibody (Fluoro647) (ABIN8035636)

Target: Senataxin (SETX)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Fluoro647

Application: Flow Cytometry (FACS)

Product Details

Binding Specificity: AA 28-2447

Purpose: Anti-SETX Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse SETX shares 72.8% amino acid (aa) sequence identity with humanSETX.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse SETX recombinant protein (Position: S28-R2447). Mouse SETX shares 72.8% amino acid (aa) sequence identity with humanSETX.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details

Target: Senataxin (SETX)

Alternative Name: SETX

Background:

Background: Predicted to enable RNA binding activity, identical protein binding activity, and transcription termination site sequence-specific DNA binding activity. Acts upstream of or within circadian rhythm and termination of RNA polymerase II transcription. Predicted to be located in several cellular components, including growth cone, intercellular bridge, and nuclear lumen. Predicted to be active in nuclear body. Is expressed in cerebral cortex ventricular layer and cortical plate. Used to study amyotrophic lateral sclerosis type 4. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 4 and spinocerebellar ataxia with axonal neuropathy 2. Orthologous to human SETX (senataxin).

Gene Full Name: senataxin

Gene ID: 269254

UniProt: A2AKX3