SH3KBP1 antibody (AA 256-629) (APC)

Catalog No. ABIN8036962

The APC-conjugated Rabbit Polyclonal anti-SH3KBP1 antibody (ABIN8036962) specifically detects SH3KBP1 in FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for SH3KBP1 antibody (AA 256-629) (APC) (ABIN8036962)

Target: SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3KBP1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-SH3KBP1 Antibody (APC)

Binding Specificity: AA 256-629

Purpose: Anti-SH3KBP1 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SH3KBP1 recombinant protein (Position: D256-Q629).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SH3KBP1

Target: SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))

Alternative Name: SH3KBP1

Background:

Background: SH3 domain-containing kinase-binding protein 1 is an adaptor protein that in humans is encoded by the SH3KBP1 gene. This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: SH3 domain containing kinase binding protein 1

Gene ID: 30011

UniProt: Q96B97

Pathways: EGFR Signaling Pathway, EGFR Downregulation