SIRT3 antibody (Middle Region) (HRP)
Quick Overview for SIRT3 antibody (Middle Region) (HRP) (ABIN8037789)
Target
See all SIRT3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Purpose
- Anti-SIRT3 Antibody HRP Conjugated
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human SIRT3, which shares 80% amino acid (aa) sequence identity with mouse and rat SIRT3.
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Isotype
- IgG
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Application Notes
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Storage
- -20 °C
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Storage Comment
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Expiry Date
- 12 months
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- SIRT3 (Sirtuin 3 (SIRT3))
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Alternative Name
- SIRT3
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Background
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Background: NAD-dependent deacetylase sirtuin-3, mitochondrial also known as SIRT3 is a protein that in humans is encoded by the SIRT3 gene. SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control.
Gene Full Name: sirtuin 3
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Gene ID
- 23410
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UniProt
- Q9NTG7
Target
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