SIRT3 antibody (AA 43-399)

Catalog No. ABIN8037804

The Rabbit Polyclonal anti-SIRT3 antibody is suitable to detect SIRT3 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for SIRT3 antibody (AA 43-399) (ABIN8037804)

Target: SIRT3 (Sirtuin 3 (SIRT3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-SIRT3 Antibody

Binding Specificity: AA 43-399

Purpose: Anti-SIRT3 Antibody

Predicted Reactivity: Human SIRT3 shares 83.5% amino acid (aa) sequence identity with mouse SIRT3.

Characteristics: Anti-SIRT3 Antibody. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SIRT3 recombinant protein (Position: R43-K399). Human SIRT3 shares 83.5% amino acid (aa) sequence identity with mouse SIRT3.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SIRT3

Target: SIRT3 (Sirtuin 3 (SIRT3))

Alternative Name: SIRT3

Background:

Background: NAD-dependent deacetylase sirtuin-3, mitochondrial also known as SIRT3 is a protein that in humans is encoded by the SIRT3 gene. SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control.

Gene Full Name: sirtuin 3

Molecular Weight: 28 kDa

Gene ID: 23410

UniProt: Q9NTG7