SIRT5 antibody (AA 81-310) (Fluoro550)

Catalog No. ABIN8037819

The Rabbit Polyclonal anti-SIRT5 antibody is suitable to detect SIRT5 in samples from Human. It has been validated for FACS.

Quick Overview for SIRT5 antibody (AA 81-310) (Fluoro550) (ABIN8037819)

Target: SIRT5 (Sirtuin 5 (SIRT5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT5 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-SIRT5 Antibody (Fluoro550)

Binding Specificity: AA 81-310

Purpose: Anti-SIRT5 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SIRT5 recombinant protein (Position: D81-S310).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SIRT5

Target: SIRT5 (Sirtuin 5 (SIRT5))

Alternative Name: SIRT5

Background:

Background: Sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae), also known as SIRT5 is a protein which in humans in encoded by the SIRT5 gene and in other species by the orthologous Sirt5 gene. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: sirtuin 5

Gene ID: 23408

UniProt: Q9NXA8

Pathways: SARS-CoV-2 Protein Interactome