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SMAD3 antibody (Middle Region) (APC)

The Rabbit Polyclonal anti-SMAD3 antibody is suitable to detect SMAD3 in samples from Human, Mouse and Rat. It has been validated for WB.
Catalog No. ABIN8038176
$840.00
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 4 to 7 Business Days

Quick Overview for SMAD3 antibody (Middle Region) (APC) (ABIN8038176)

Target

See all SMAD3 Antibodies
SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Reactivity

  • 274
  • 126
  • 100
  • 13
  • 12
  • 9
  • 8
  • 7
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Mouse, Rat

Host

  • 259
  • 29
  • 1
Rabbit

Clonality

  • 219
  • 70
Polyclonal

Conjugate

  • 141
  • 17
  • 13
  • 11
  • 10
  • 6
  • 6
  • 6
  • 6
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  • 6
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  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
This SMAD3 antibody is conjugated to APC

Application

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  • 91
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  • 87
  • 57
  • 57
  • 53
  • 38
  • 17
  • 10
  • 8
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 54
    • 49
    • 29
    • 29
    • 28
    • 12
    • 11
    • 11
    • 8
    • 6
    • 6
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    • 5
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Purpose

    Anti-Smad3 Antibody APC Conjugated

    Specificity

    No cross reactivity with other proteins.

    Cross-Reactivity (Details)

    No cross-reactivity with other proteins.

    Predicted Reactivity

    identical to the related mouse,rat sequences.

    Purification

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence in the middle region of human Smad3, identical to the related mouse and rat sequences.

    Isotype

    IgG
  • Application Notes

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

    Comment

    Applications are recommended based on the unconjugated antibody.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    Expiry Date

    12 months
  • Target

    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

    Alternative Name

    SMAD3

    Background

    Background: Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. SMAD3 is a member of the SMAD family of proteins. It is located in 15q22.33. And it mediates the signals from the transforming growth factor beta (TGF-β) super family ligands that regulate cell proliferation, differentiation and death. Based on its essential role in TGF beta signaling pathway, SMAD3 has been related with tumor growth in cancer development.

    Gene Full Name: SMAD family member 3

    Sequence Similarities: Belongs to the dwarfin/SMAD family.

    Gene ID

    4088

    UniProt

    P84022

    Pathways

    Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
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