SMAD3 antibody (Middle Region) (APC)
Quick Overview for SMAD3 antibody (Middle Region) (APC) (ABIN8038176)
Target
See all SMAD3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- Middle Region
-
Purpose
- Anti-Smad3 Antibody APC Conjugated
-
Specificity
- No cross reactivity with other proteins.
-
Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
-
Predicted Reactivity
- identical to the related mouse,rat sequences.
-
Purification
- Immunogen affinity purified.
-
Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human Smad3, identical to the related mouse and rat sequences.
-
Isotype
- IgG
-
-
-
-
Application Notes
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
-
Comment
-
Applications are recommended based on the unconjugated antibody.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
Expiry Date
- 12 months
-
-
- SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
-
Alternative Name
- SMAD3
-
Background
-
Background: Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. SMAD3 is a member of the SMAD family of proteins. It is located in 15q22.33. And it mediates the signals from the transforming growth factor beta (TGF-β) super family ligands that regulate cell proliferation, differentiation and death. Based on its essential role in TGF beta signaling pathway, SMAD3 has been related with tumor growth in cancer development.
Gene Full Name: SMAD family member 3
Sequence Similarities: Belongs to the dwarfin/SMAD family.
-
Gene ID
- 4088
-
UniProt
- P84022
-
Pathways
- Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
Target
-