SNRNP200 antibody (AA 557-2129) (Fluoro488)

Catalog No. ABIN8038270

The Fluoro488-conjugated Rabbit Polyclonal anti-SNRNP200 antibody (ABIN8038270) specifically detects SNRNP200 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SNRNP200 antibody (AA 557-2129) (Fluoro488) (ABIN8038270)

Target: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRNP200 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-SNRNP200 Antibody (Fluoro488)

Binding Specificity: AA 557-2129

Purpose: Anti-SNRNP200 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SNRNP200 recombinant protein (Position: K557-A2129).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SNRNP200

Target: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Alternative Name: SNRNP200

Background:

Background: U5 small nuclear ribonucleoprotein 200 kDa helicase is an enzyme that in humans is encoded by the SNRNP200 gene. Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Gene Full Name: small nuclear ribonucleoprotein U5 subunit 200

Gene ID: 23020

UniProt: O75643

Pathways: Ribonucleoprotein Complex Subunit Organization