SNRPC antibody (AA 1-159) (Biotin)

Catalog No. ABIN8038356

The Rabbit Polyclonal anti-SNRPC antibody is suitable to detect SNRPC in samples from Human, Rat and Mouse. It has been validated for WB, IHC and ELISA.

Quick Overview for SNRPC antibody (AA 1-159) (Biotin) (ABIN8038356)

Target: SNRPC (Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRPC antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-SNRPC Antibody (Biotin)

Binding Specificity: AA 1-159

Purpose: Anti-U1-C/SNRPC Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human U1-C/SNRPC recombinant protein (Position: M1-R159).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SNRPC

Target: SNRPC (Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC))

Alternative Name: SNRPC

Background:

Background: U1 small nuclear ribonucleoprotein C is a protein that in humans is encoded by the SNRPC gene. This gene encodes one of the specific protein components of the U1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. The encoded protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases. The genome contains several pseudogenes of this functional gene. Alternative splicing results in a non-coding transcript variant.

Gene Full Name: small nuclear ribonucleoprotein polypeptide C

Gene ID: 6631

UniProt: P09234

Pathways: Ribonucleoprotein Complex Subunit Organization