SMO antibody (AA 476-764) (Biotin)

Catalog No. ABIN8038545

The Rabbit Polyclonal anti-SMO antibody is suitable to detect SMO in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for SMO antibody (AA 476-764) (Biotin) (ABIN8038545)

Target: SMO (Smoothened Homolog (Drosophila) (SMO))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMO antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SMO Antibody (Biotin)

Binding Specificity: AA 476-764

Purpose: Anti-Smoothened/SMO Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Smoothened/SMO recombinant protein (Position: N476-Q764).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SMO

Target: SMO (Smoothened Homolog (Drosophila) (SMO))

Alternative Name: SMO

Background:

Background: Smoothened is a protein that in humans is encoded by the SMO gene. The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.

Gene Full Name: smoothened, frizzled class receptor

Gene ID: 6608

UniProt: Q99835

Pathways: Hedgehog Signaling