SLC26A4 antibody (C-Term)

Catalog No. ABIN8040001

The Rabbit Polyclonal anti-SLC26A4 antibody (ABIN8040001) specifically detects SLC26A4 in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for SLC26A4 antibody (C-Term) (ABIN8040001)

Target: SLC26A4 (Solute Carrier Family 26, Member 4 (SLC26A4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC26A4 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-SLC26A4 Antibody

Binding Specificity: C-Term

Purpose: Anti-SLC26A4 Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SLC26A4 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SLC26A4, which shares 84.4% amino acid (aa) sequence identity with both mouse and rat SCNN1A.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SLC26A4

Target: SLC26A4 (Solute Carrier Family 26, Member 4 (SLC26A4))

Alternative Name: SLC26A4

Background:

Background: Pendrin, is an anion exchange protein that in humans is encoded by the SLC26A4 gene. Pendrin is an ion exchanger found in many types of cells in the body. High levels of pendrin expression have been identified in the inner ear and thyroid. In the thyroid, pendrin mediates a component of the efflux of iodide across the apical membrane of the thyrocyte, which is critical for the formation of thyroid hormone. The exact function of pendrin in the inner ear remains unclear, however, pendrin may play a role in acid-base balance as a chloride-bicarbonate exchanger, regulate volume homeostasis through its ability to function as a chloride-formate exchanger or inly modulate the calcium concentration of the endolymph.

Gene Full Name: solute carrier family 26 member 4

Molecular Weight: 86 kDa

Gene ID: 5172

UniProt: O43511

Pathways: Thyroid Hormone Synthesis, Sensory Perception of Sound