SNX15 antibody (AA 8-327) (HRP)

Catalog No. ABIN8040926

This Rabbit Polyclonal antibody specifically detects SNX15 in ELISA, WB and IHC. It exhibits reactivity toward Human.

Quick Overview for SNX15 antibody (AA 8-327) (HRP) (ABIN8040926)

Target: SNX15 (Sorting Nexin 15 (SNX15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX15 antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SNX15 Antibody (HRP)

Binding Specificity: AA 8-327

Purpose: Anti-SNX15 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SNX15 recombinant protein (Position: D8-K327).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SNX15

Target: SNX15 (Sorting Nexin 15 (SNX15))

Alternative Name: SNX15

Background:

Background: Sorting nexin-15 is a protein that in humans is encoded by the SNX15 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

Gene Full Name: sorting nexin 15

Gene ID: 29907

UniProt: Q9NRS6