Spectrin beta Chain, Erythrocyte (SPTB) (AA 703-2137) antibody

Catalog No. ABIN8041385

This Rabbit Polyclonal antibody specifically detects Spectrin beta Chain, Erythrocyte in WB, FACS and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Spectrin beta Chain, Erythrocyte (SPTB) (AA 703-2137) antibody (ABIN8041385)

Target: Spectrin beta Chain, Erythrocyte (SPTB)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Grade: Carrier-free

Product Details

Binding Specificity: AA 703-2137

Purpose: Anti-beta 1 Spectrin/SPTB Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-beta 1 Spectrin/SPTB Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human beta 1 Spectrin/SPTB recombinant protein (Position: M703-Y2137).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: Spectrin beta Chain, Erythrocyte (SPTB)

Alternative Name: SPTB

Background:

Background: Spectrin beta chain, erythrocyte is a protein that in humans is encoded by the SPTB gene. This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described.

Gene Full Name: spectrin beta, erythrocytic

Molecular Weight: 270 kDa

Gene ID: 6710

UniProt: P11277

Pathways: Regulation of Actin Filament Polymerization