SYNE2 antibody (AA 3765-5590) (Biotin)

Catalog No. ABIN8041386

The Rabbit Polyclonal anti-SYNE2 antibody is suitable to detect SYNE2 in samples from Human and Monkey. It has been validated for WB, ELISA and IHC.

Quick Overview for SYNE2 antibody (AA 3765-5590) (Biotin) (ABIN8041386)

Target: SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNE2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SYNE2 Antibody (Biotin)

Binding Specificity: AA 3765-5590

Purpose: Anti-Nesprin 2/SYNE2 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Nesprin 2/SYNE2 recombinant protein (Position: Q3765-Q5590).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SYNE2

Target: SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))

Alternative Name: SYNE2

Background:

Background: Nesprin-2 is a protein that in humans is encoded by the SYNE2 gene. The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: spectrin repeat containing nuclear envelope protein 2

Gene ID: 23224

UniProt: Q8WXH0

Pathways: Maintenance of Protein Location