SPATA18 antibody (AA 27-490) (HRP)

Catalog No. ABIN8041547

This Rabbit Polyclonal antibody specifically detects SPATA18 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for SPATA18 antibody (AA 27-490) (HRP) (ABIN8041547)

Target: SPATA18 (Spermatogenesis Associated 18 (SPATA18))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPATA18 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SPATA18 Antibody (HRP)

Binding Specificity: AA 27-490

Purpose: Anti-SPATA18 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SPATA18 recombinant protein (Position: E27-R490).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SPATA18

Target: SPATA18 (Spermatogenesis Associated 18 (SPATA18))

Alternative Name: SPATA18

Background:

Background: This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants.

Gene Full Name: spermatogenesis associated 18

Gene ID: 132671

UniProt: Q8TC71