SMOX antibody (AA 40-555)

Catalog No. ABIN8041640

This Rabbit Polyclonal antibody specifically detects SMOX in ELISA, WB and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SMOX antibody (AA 40-555) (ABIN8041640)

Target: SMOX (Spermine Oxidase (SMOX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMOX antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-SMOX Antibody

Binding Specificity: AA 40-555

Purpose: Anti-SMOX Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SMOX Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse SMOX recombinant protein (Position: A40-P555).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SMOX

Target: SMOX (Spermine Oxidase (SMOX))

Alternative Name: Smox

Background:

Background: Spermine oxidase is an enzyme that in humans is encoded by the SMOX gene. It is mapped to 2, 2 F1. Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism.

Gene Full Name: spermine oxidase

Molecular Weight: 62 kDa

Gene ID: 228608

UniProt: Q99K82