SYK antibody (AA 10-635) (Cy3)
Quick Overview for SYK antibody (AA 10-635) (Cy3) (ABIN8041808)
Target
See all SYK AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 10-635
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Purpose
- Anti-SYK Antibody Cy3 Conjugated
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Specificity
- No cross reactivity with other proteins.
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human SYK recombinant protein (Position: A10-N635).
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Isotype
- IgG
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Application Notes
- Flow Cytometry, 1-3 μg/1x106 cells
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Expiry Date
- 12 months
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- SYK (Spleen tyrosine Kinase (SYK))
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Alternative Name
- SYK
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Background
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Background: Spleen tyrosine kinase, also known as Syk, is an enzyme which in humans is encoded by the SYK gene. It is mapped to 9q22.2. This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: spleen associated tyrosine kinase
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Gene ID
- 6850
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UniProt
- P43405
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Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
Target
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