SOX7 antibody (AA 57-343) (Fluoro488)

Catalog No. ABIN8042363

This Rabbit Polyclonal antibody specifically detects SOX7 in FACS. It exhibits reactivity toward Human.

Quick Overview for SOX7 antibody (AA 57-343) (Fluoro488) (ABIN8042363)

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX7 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-SOX7 Antibody (Fluoro488)

Binding Specificity: AA 57-343

Purpose: Anti-SOX7 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SOX7 recombinant protein (Position: K57-D343).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SOX7

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Alternative Name: SOX7

Background:

Background: SOX7 belongs to SOX gene family and SOX proteins are transcription factors with critical roles in the regulation of diverse developmental processes. This gene is mapped to 8p23.1. SOX7 gene contains at least 2 exons. In cotransfected 293 cells, Sox7 reduced Wnt (see WNT1)/beta-catenin (see CTNNB1)- stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.

Gene Full Name: SRY-box transcription factor 7

Gene ID: 83595

UniProt: Q9BT81

Pathways: Positive Regulation of Endopeptidase Activity