SOX7 antibody (C-Term) (APC)

Catalog No. ABIN8042379

The Rabbit Polyclonal anti-SOX7 antibody is suitable to detect SOX7 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for SOX7 antibody (C-Term) (APC) (ABIN8042379)

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX7 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-SOX7 Antibody (APC)

Binding Specificity: C-Term

Purpose: Anti-SOX7 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SOX7, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SOX7

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Alternative Name: SOX7

Background:

Background: SOX7 belongs to SOX gene family and SOX proteins are transcription factors with critical roles in the regulation of diverse developmental processes. This gene is mapped to 8p23.1. SOX7 gene contains at least 2 exons. In cotransfected 293 cells, Sox7 reduced Wnt (see WNT1)/beta-catenin (see CTNNB1)- stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.

Gene Full Name: SRY-box transcription factor 7

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

Gene ID: 83595

UniProt: Q9BT81

Pathways: Positive Regulation of Endopeptidase Activity