SOX9 antibody (AA 1-496) (APC)

Catalog No. ABIN8042401

The APC-conjugated Rabbit Polyclonal anti-SOX9 antibody (ABIN8042401) specifically detects SOX9 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SOX9 antibody (AA 1-496) (APC) (ABIN8042401)

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX9 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-SOX9 Antibody (APC)

Binding Specificity: AA 1-496

Purpose: Anti-SOX9 Antibody APC Conjugated

Predicted Reactivity: Human SOX9 shares 97%,96% amino acid (aa) sequence identity with mouse,rat SOX9,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SOX9 recombinant protein (Position: M1-Q496). Human SOX9 shares 97% and 96% amino acid (aa) sequence identity with mouse and rat SOX9, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Alternative Name: SOX9

Background:

Background: Transcription factor SOX-9 is a protein that in humans is encoded by the SOX9 gene. The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

Gene Full Name: SRY-box transcription factor 9

Gene ID: 6662

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development