SRA1 antibody (AA 1-224) (FITC)

Catalog No. ABIN8042768

This Rabbit Polyclonal antibody specifically detects SRA1 in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for SRA1 antibody (AA 1-224) (FITC) (ABIN8042768)

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRA1 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-SRA1 Antibody (FITC)

Binding Specificity: AA 1-224

Purpose: Anti-SRA1 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SRA1 shares 81.8%,80% amino acid (aa) sequence identity with mouse,rat SRA1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SRA1 recombinant protein (Position: M1-S224). Human SRA1 shares 81.8% and 80% amino acid (aa) sequence identity with mouse and rat SRA1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SRA1

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Alternative Name: SRA1

Background:

Background: Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA.

Gene Full Name: steroid receptor RNA activator 1

Gene ID: 10011

UniProt: Q9HD15

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development