SRA1 antibody (AA 1-224)

Catalog No. ABIN8042773

The Rabbit Polyclonal anti-SRA1 antibody (ABIN8042773) specifically detects SRA1 in WB, ELISA, FACS, IF and ICC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for SRA1 antibody (AA 1-224) (ABIN8042773)

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-SRA1 Antibody

Binding Specificity: AA 1-224

Purpose: Anti-SRA1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SRA1 shares 81.8%,80% amino acid (aa) sequence identity with mouse,rat SRA1,respectively.

Characteristics: Anti-SRA1 Antibody. Tested in WB, ICC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SRA1 recombinant protein (Position: M1-S224). Human SRA1 shares 81.8% and 80% amino acid (aa) sequence identity with mouse and rat SRA1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SRA1

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Alternative Name: SRA1

Background:

Background: Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA.

Gene Full Name: steroid receptor RNA activator 1

Molecular Weight: 33 kDa

Gene ID: 10011

UniProt: Q9HD15

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development