SOAT1 antibody (AA 41-548) (Biotin)

Catalog No. ABIN8042829

The Rabbit Polyclonal anti-SOAT1 antibody is suitable to detect SOAT1 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for SOAT1 antibody (AA 41-548) (Biotin) (ABIN8042829)

Target: SOAT1 (Sterol O-Acyltransferase 1 (SOAT1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOAT1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SOAT1 Antibody (Biotin)

Binding Specificity: AA 41-548

Purpose: Anti-SOAT1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human SOAT1 shares 88.2%,87.4% amino acid (aa) sequence identity with mouse,rat SOAT1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SOAT1 recombinant protein (Position: R41-Y548). Human SOAT1 shares 88.2% and 87.4% amino acid (aa) sequence identity with mouse and rat SOAT1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SOAT1

Target: SOAT1 (Sterol O-Acyltransferase 1 (SOAT1))

Alternative Name: SOAT1

Background:

Background: Sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1, also known as SOAT1, is an enzyme that in humans is encoded by the SOAT1 gene. The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: sterol O-acyltransferase 1

Gene ID: 6646

UniProt: P35610