SOCS5 antibody (AA 386-536) (Fluoro488)

Catalog No. ABIN8043780

The Rabbit Polyclonal anti-SOCS5 antibody is suitable to detect SOCS5 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for SOCS5 antibody (AA 386-536) (Fluoro488) (ABIN8043780)

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS5 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-SOCS5 Antibody (Fluoro488)

Binding Specificity: AA 386-536

Purpose: Anti-SOCS5 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SOCS5 recombinant protein (Position: M386-K536).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SOCS5

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Alternative Name: SOCS5

Background:

Background: Suppressor of cytokine signaling 5 is a protein that in humans is encoded by the SOCS5 gene. It is mapped to 2p21. The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

Gene Full Name: suppressor of cytokine signaling 5

Gene ID: 9655

UniProt: O75159

Pathways: JAK-STAT Signaling, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process